Turkish Scientists Have Succeeded To Synthesize Malaria Drugs Used In The Treatment Of COVID-19


Researchers from the Middle East Technical University (METU) succeeded in synthesizing the malaria drug chlorokine, which is used in the treatment of COVID-19, with local facilities in 10 days.

While the new type of coronavirus (COVID-19) epidemic continues to darken thousands of lives every day, the world of science continues to work day and night to find an effective treatment method against this deadly virus. Turkish scientists also make very important contributions to this process with their work.

METU Science and Letters Faculty Chemistry Department Faculty Member Assoc. Dr. Akın Akdağ stated that they managed to synthesize the chloroquine drug used for the prevention and treatment of malaria species with simple means in the laboratory with domestic facilities.

The drug used in the treatment of COVID-19 was synthesized by domestic means
Assoc. Dr. Akdağ said that in many countries, hydroxychloroquine and chloroquine drugs, previously prescribed as malaria medicines, are allowed to be used in the treatment of COVID-19. Stating that they conducted experimental studies in the laboratory to develop a method that would allow localization of the raw material production of this drug, the researcher stated that they first examined the structure of chlorokinin.

Doctorate student Gizem Ünay, graduate students Doruk Baykal, Berçin Asya and Umut Aydemir stated that they are working to synthesize the active substances in chlorokinin from two different branches. Dr. Akdağ stated that they managed to synthesize this substance in 10 days starting from completely simple starting materials with local possibilities.

It took 10 days to synthesize chlorokine, known as malaria drug.
As it is experimental, Assoc said that they synthesize a small amount of chloroquine using only the materials in the laboratories. Dr. “If we can find project support to meet the needs of our laboratory for certain substances, our hopes have increased that we can produce larger quantities,” said Akdag.

“There are also some steps that are not found in the literature in our method,” said the Turkish scientist, “We have many patented methods in the synthesis of chlorocine. We have started preparations for international publications for this.

Many countries allow the use of hydroxychloroquine and chloroquine drugs in the treatment of COVID-19
In our previous report, we shared with you the statement of Sanofi, one of the world’s leading pharmaceutical laboratories based in France, that 300,000 COVID-19 patients can be treated with the hydroxychloroquine drug used for malaria.

Professor Didier Raoult, at the University of Marseille Medical School, who led the work carried out by Sanofi, said that 24 COVID-19 patients were treated with the drug in question, and that the virus disappeared in 75 percent of cases six days later.


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