A group of researchers at the Massachusetts Institute of Technology (MIT) has so far used artificial intelligence to identify a new antibiotic that has killed even antibiotic resistant structures.
A Scottish scientist named Sir Alexander Fleming left his lab where he studied staphylococcus bacteria in 1928 and went on a two-week vacation with his family. When he returned to the lab, Fleming noticed that he had not only arranged the working area very well, but that food containing bacteria was moldy. He also noticed that bacteria seemed to be actively avoiding moldy areas of the cell culture dish.
After all this, Fleming said, “I had not planned to revolutionize all drugs by discovering the world’s first antibiotic or bacteria killer. I think I did exactly that. ” These days, discovering new antibiotics does not require a careless and negligent scientist.
Artificial intelligence was used in the discovery of antibiotics:
A group of researchers working at MIT used artificial intelligence to discover a new antibiotic that even killed antibiotic-resistant structures. The research team created a computer model that systematically scans over a hundred million chemical compounds in just a few days.
“We are facing a growing crisis around antibiotic resistance,” said Professor James Collins of MIT. This is due to the number of pathogens that have become resistant to existing antibiotics, ”he says. The research team has developed a machine learning model that can identify about 2,500 molecular compounds that inhibit the growth of bacteria.
Antibiotic study from scientists:
The program was introduced to 6,000 drugs currently under review to see if they are beneficial in treating known human diseases. After the model selected the molecule with the strongest antibacterial potential unlike any known antibiotic, the team used a different model to see if the molecule would harm humans.
The model reduced the candidates to one. It was the chemical component that the researchers called ‘halisin’. Halisin was originally investigated for the treatment of diabetes, but this study did not continue due to poor test results.
After the carpet was discovered, the research team identified 23 more candidates using another compound database, two of which came out strong. Researchers are now working to find antibiotics that are more selective in bacteria, and in doing so they retain all of our beneficial gut flora. As it stands, researchers plan to work with a pharmaceutical company or nonprofit to develop the drug for use in humans.