Researchers are working on a protein that reveals the beneficial effects of exercise
Scientists are working on a protein in the human body that will bring out the beneficial effects of exercise. This protein, called cestrin, can help prevent muscle loss and stay in shape.
A quick walk around the park or a high intensity workout at the gym keeps the body fit. What if we could benefit from a good workout without exercising our muscles? Scientists may have found a way to keep the body in shape without training.
Researchers at the University of Michigan have found that a naturally occurring class of proteins, Sestrin, can greatly mimic the effects of exercise in flies and mice. The findings may ultimately help scientists fight muscle loss due to effects such as aging. Myungjin Kim, an associate professor at the Department of Molecular and Integrative Physiology, said researchers had previously observed that Sestrin accumulates in muscle after exercise.
This protein can enable us to have an exercise body without exercise
Kim, professor Jun Hee Lee, and a group of researchers wanted to learn more about the exercise effect of protein, and they first started working on flies. Taking advantage of the climbing and climbing instinct in the test tube of flies of the genus Drosophila, the researchers developed a kind of treadmill for flies. The team trained the flies for about 3 weeks and compared their running and flying abilities with those of the cestrin-hindered flies.
Cestrin flies were able to run for about 4 to 6 hours, while their ability was found to improve. Flies without sestrins did not develop with exercise. The beneficial effects of Sestrin include more than enhanced durability. For example, in mice lacking sestrine, there was typically no exercise-related aerobic capacity, respiration and fat burning.
Can sestrin supplements be on the horizon? According to Lee, the answer is ‘no’ for now. Scientists still don’t know how exercise produces cestrin in the body, and cestrins are not small molecules. Researchers are working to find small molecule regulators of protein. Studies can be used as a treatment or fitness for people who cannot exercise in the future.