Researchers Explore A Zone In The Brain That Controls Excessive Alcohol Consumption

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Engraving brain illustration in grayscale monochrome color on white background

A new study by the South Carolina Medical University in the USA discovered a region in the brain that controls excessive alcohol consumption. Scientists have observed that disabling the stress-signal system in the area in question can reduce excessive alcohol use.

According to the data of World Health Organization (WHO), 6 percent (3.3 million) of all deaths in the world occur due to alcohol use. The degree of alcohol consumption, which causes important problems not only in the liver but also in the brain, causes impaired ability to think, make decisions and act.

In a new study by the University of South Carolina Medical University, scientists have tested a potential strategy to reduce excessive alcohol use. “Thanks to our study, we found a brain region and a system that we can manipulate to reduce excessive alcohol consumption,” said graduate student JR Haun, one of the authors of the study.

“We found a brain region that we can manipulate to reduce excessive alcohol consumption”
Scientists investigating the opioid-receptor system influenced by drugs such as morphine, heroin, and oxycontin / oxycodone have reached quite interesting findings. Dr. Charleston Alcohol Research Center director. Howard Becker stated that these and similar receptors can be intervened to help suppress the desire and excessive desire to drink in individuals.

However, he emphasized that there is another receptor system called kappa-opioid, which is not related to enjoyable signals and is associated with feelings of stress and discontent. Becker stated that this is the antithesis of other opioid receptors and is often described as a counter-reward system.

The findings can contribute to future chronic alcoholism treatments.
He stated that the reason why people feel relieved after drinking alcohol is the activated opioid receptors. Becker said that subsequent discomfort such as nausea and headache was caused by the kappa-opioid receptor.

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Scientists who observed that deactivating the cappa-opioid receptors in Amigdala, a almond-shaped brain section formed by neurons located deep inside the medial temporal lobe of the brain, was not only associated with feelings of stress and discontent.

Stating that blocking kappa-opioid receptors in the amygdala can act as a therapy to reduce excessive alcohol use. Becker emphasized that their findings can make a significant contribution to future chronic alcoholism treatments.


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