Biologists Try to Produce Corona Virus in Lab Environment

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Scientists continue their efforts to cope with the Corona virus epidemic, which has spread around the world and cost more than 1,600 people after it emerged in China. Biologists are trying to reproduce it in laboratory conditions using the DNA code of the Corona virus.

Scientists have mobilized to combat the Corona virus, which has spread after the appearance in Wuhan, People’s Republic of China, causing 1,670 deaths so far. One of the important elements of the fight against the virus is to decode its DNA and reproduce the virus in the laboratory. The production of the synthetic version of the deadly virus can be an important door for the treatments tested.

The University of North Carolina lab is trying to reproduce it from the DNA sequence of the virus, which is published online by China. Companies such as Integrated DNA Technology, Twist Bioscience and Atum are pioneers in copying viruses. If the correct genes can be sequenced and these genes are ‘stitched’ together, the Corona virus genome is reproduced, experts can quickly inject this genetic material into the cells and start tracking viruses.

Synthetic Corona virus will be produced in 1 month:
The activity of a deadly virus to reproduce it using the DNA code began about 20 years ago. Companies doing this job because of the concern of bio-terrorism closely follow who placed the order. However, reproducing the virus provides a tremendous trump in cases such as the vaccine, the fight against the epidemic, and the treatment of the disease in cases of the sudden epidemic caused by the virus.

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Ralph Baric of the University of North Carolina says they received an order last month to reproduce the deadly Corona virus in a laboratory setting. For this, Baric et al. Started by comparing Corona virus genomes on the internet and choosing a decided version. It is stated that it will take a month to obtain synthetic DNA. After this process, genetic material will be injected into the cells.

Thanks to the production of synthetic virus DNA, scientists can add and remove genes into the genome of the virus as they wish, and thus determine how the virus enters the human cell. For this, experiments are expected on mice. In addition, synthetic viruses give researchers the ability to make predictions about how to react when the virus is mutated.

DNA manufacturers also take measures to prevent deadly viruses from falling into the wrong hands. Companies in the US have joined forces to prevent access to ‘dangerous genes’.


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