8 Details About Pfizer’s Promising Coronavirus Vaccine


BioNTech and pharmaceutical giant Pfizer, founded by two Turkish doctors living in Germany, recently announced that they have achieved 90% success in the coronavirus vaccine. We are looking closely at the details of this development and Pfizer’s coronavirus vaccine, which gives hope to the whole world.

Everyone is anxiously and excitedly waiting for ways to get rid of the Covid-19 epidemic that has affected the whole world. A piece of news that could give hope to the whole world came from a pharmaceutical company called Pfizer recently.

Pfizer, founders of the Turkish doctor Uğur Şahin and his wife Dr. The company named BioNTech, based in Germany, which is Özlem Türeci, started coronavirus vaccine studies long ago. The vaccine does show promise, according to recent tests. So when will Pfizer’s coronavirus vaccine be released, how will it be applied? Let’s take a closer look at the details and success rates about the vaccine.

1. Turkish doctors Uğur Şahin and Özlem Türeci have a big share in vaccination:

BioNTech co-founder and CEO Uğur Şahin said in his statement that he realized that this virus would affect everyone when Covid-19 started to spread in Europe, that is, towards the end of January. Prof. Dr. Uğur Şahin and Özlem Türeci, who is also a doctor and sitting in the CMO chair of the company, formed a group of 40 people after the first case was seen in France and the vaccine studies called Project Lightspeed started quickly.

BioNTech, as a result of long researches, began to design 20 different vaccines and try it on rodents, but unfortunately the company did not have enough resources to conduct a long-term clinical trial. The company partnered with Pfizer in mid-March to continue research and develop the vaccine.

2. How did the groundbreaking Phase-3 experiments in Pfizer’s vaccine start, how did they end up?

Pfizer and BioNTech administered vaccines to approximately 39,000 volunteers who were not previously diagnosed with Covid-19 in their Phase-3 experiments. Turkey, including the medical history of their candidates to be different from each other that allows participation from various countries, stated that the vaccine played a major role in the success rate shows.

In order to successfully observe the effect of the vaccine, all candidates were divided into two groups. One group received two doses of vaccine, while the other group received only saline to observe the placebo effect. However, it was soon proven that the success was due to the vaccine itself, not the placebo effect.

As a result of the experiments, it is observed that the administration of two doses of the vaccine with an interval of 1 week allows 90% of the candidates to be immune to the virus, and no side effects are observed. So far, 38,955 people have been vaccinated, and among these candidates, only 164 people have been infected with Covid-19 disease.

3. The vaccine was tested in Turkey:

As we mentioned before, trials of the vaccine were made through candidates from different countries. There were also Turkey in these countries. How many doses of the vaccine was applied in Turkey and also been announced as to who are called on, we think that Germany and the United States followed the same path followed by roads.

Pfizer started to test the vaccine in the USA after his experiments in Germany. In this experiment, conducted with candidates at the medical schools of Maryland and New York Universities, the vaccine was first administered to people between the ages of 18 and 55. When it was determined that there was no health problem in these people, they started applying the vaccine to candidates aged 65-85.

4. How many million doses of Pfizer’s coronavirus vaccine will be produced?

Pfizer stated that if the Covid-19 vaccine is successful as expected, they will be able to produce a total of 40-50 million doses of vaccine towards the end of 2020. This vaccine can be administered to approximately 20-25 million people, since applying the vaccine twice in one week brings the most successful result. This shows that the vaccine is currently available to people in high risk groups, such as healthcare workers.

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In 2021, the dose rate will increase to 1.3 billion. Although the year 2021 is marked to slow down the epidemic globally, it is said that Pfizer’s vaccine alone will not be enough, and other vaccination studies should be successful and implemented as soon as possible.

5. When will Pfizer’s coronavirus vaccine be released?

Pfizer stated that they expect approval from the FDA, the US Food and Drug Administration, before launching the vaccine. The FDA says they expect at least 50% success rate from candidates participating in final phase trials before approving a vaccine, and that people who receive the vaccine should follow up for at least two months.

Pfizer’s Covid-19 vaccine will be approved by the FDA if the vaccine does not have health problems such as neurological or heart disease in people who are administered the vaccine and if 50 percent success is achieved in the experiments. With a 90% success rate, Pfizer is currently preparing to apply for FDA approval in the last days of this two-month follow-up and in the coming days.

6. How does the Pfizer vaccine affect coronavirus?

Pfizer’s vaccine injects a genetic material called mRNA into the human body. This mRNA communicates with cells responsible for protein production, and cells are triggered to produce the spike protein found in the outer wall of the Covid-19 virus. The human body begins to produce antibodies in response to these spike proteins, so that the person being vaccinated becomes immune to the infection.

7. Should we really get excited?

While most experts, scientists and doctors agree that the vaccine is an extremely exciting development, it is too early to be happy with the vaccine news. It should also be noted that the results from Pfizer are preliminary and only some of the results are shared.

As we mentioned before, only 164 positive corona cases were detected among the 38,955 candidates who were vaccinated. Although the vaccine creates immunity against Covid-19 in humans, it is still a mystery how it will cause side effects in the future. For this reason, Pfizer stated that they will follow the people to be vaccinated for 2 years.

Another factor that will discourage our enthusiasm is that it is still unknown how long the vaccine will be effective. In other words, how long the person becomes immune after the vaccine is administered, is not yet known. In addition, since the vaccine has been administered only to people who have not previously caught Covid-19, it is among the unanswered questions whether the vaccine will be effective in patients with a history of Covid-19.

8. Will the vaccine get us back to normal?

Along with the vaccine of Pfizer and BioNTech, other vaccine candidates expect to be successful and start mass production by the end of the year. However, production is expected to be extremely limited, as all vaccine approvals mark the end of the year at the earliest.

With the limited production, as we have mentioned before, the vaccine can be applied only to people in the high risk group at first. Authorities emphasize that they do not expect a global vaccine implementation by the summer of 2021, and say that we should continue to rigorous measures in the coming year.

So, as a result, we need to wait a little longer to get rid of social distance and the mask and never let go of the precaution. An infectious disease specialist at Johns Hopkins University, Dr. “We must double our efforts to prevent infection while waiting for the cure method and the vaccine,” says Lisa Maragakis.


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